![]() ![]() These studies can be important in improving diagnostics and therapeutic applications. Experiments on hemodynamic effects in elastic silicon rubber models of the cardiovascular system with flow wire, stents, or patches for vessel surgery will be discussed. These deposits are found predominantly at arterial bends and bifurcations where blood flow is disturbed, where a secondary flow is created, and where flow separation regions are found. The interaction between blood cells and of the cells with the vessel, leads to the formation of plaques and agglomerations. These mechanical factors are largely responsible for the deposit of blood cells and lipids, a leading cause of atherosclerosis. Health care practitioners must understand fluid dynamic factors such as flow rate ratio, pressure and velocity gradients, and flow behavior, velocity distribution, shear stress on the wall and on blood cells. High velocity fluctuations indicate flow disturbances that should be avoided. In preliminary studies, it has been demonstrated that geometry and elasticity of vessel walls help determine flow behavior. ![]() Other factors such as vessel wall structure are also important. Joseph Bull, Tulane University ‘Professor Grotberg’s new Biofluid Mechanics textbook is a comprehensive volume building from basics (kinematics, conservation of mass and momentum) to advanced topics (flow in flexible tubes, porous media and many others). Experiments have shown that hemodynamics may have a strong influence on the creation of aneurysms and varicose veins. Viscosity and flow behavior changes specifically the creation of vortices and flow disturbances can be used to show how medication can influence flow behavior. Measurement techniques for model studies such as LDA, ultrasound, and MRI studies will be discussed. Fundamental fluid mechanical, which are important for the understanding of the blood flow in the cardiovascular circulatory system of the human body aspects are presented. Biofluid mechanics play a major role in the cardiovascular system and it is important to understand the forces and movement of blood cells and whole blood as well as the interaction between blood cells and the vessel wall. Complex hemodynamics play a critical role in the development of atherosclerosis and the processes of aging, as well as many other disease processes. Cardiovascular disease is the primary cause of morbidity and mortality in the western world. ![]()
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